Product Identification
【Product Name】Minolteparin sodium
【Synonyms】Ardeparin sodium；肝素钠
【CAS】9041-08-1
【RTECS】MI0850000
【RTECS Class】Drug; Human Data
【Merck】13,4670
【Beilstein/Gmelin】NA

Physical and Chemical Properties
【Appearance】Odorless white to off-white solid or liquid
【Usage】Anticlotting agent.

First Aid Measures
【Ingestion】Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
【Inhalation】Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear.
【Skin】Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse.
【Eyes】Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage
【Storage】Keep from freezing. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
【Handling】Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Avoid contact with skin and eyes. Keep container tightly closed. Avoid ingestion and inhalation.

Hazards Identification
【Ingestion】May cause gastrointestinal irritation with nausea, vomiting and diarrhea. Low hazard for usual industrial handling.
【Inhalation】May cause respiratory tract irritation. Low hazard for usual industrial handling.
【Skin】May cause skin irritation. Substance is an anticoagulant. Exposure by injection may cause hemorrhage at multiple sites, respiratory and kidney abnormalities, anemia, and cardiovascular collapse. May cause erythema, and edema with crusting and scaling.
【Eyes】Contact may cause transient eye irritation.
【EC Safety Phrase】S 22 24/25

Exposure Controls/Personal Protection
【Personal Protection】Eyes: Wear appropriate protective eyeglasses or chemical safety ggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
【Respirators】A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
【Poison Class】3

Fire Fighting Measures
【Fire Fighting】Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Non-combustible, substance itself does not burn but may decompose upon heating to produce irritating, corrosive and/or toxic fumes. Extinguishing media: Substance is noncombustible; use agent most appropriate to extinguish surrounding fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.

Accidental Release Measures
【Small spills/leaks】Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Absorb spill using an absorbent, non-combustible material such as earth, sand, or vermiculite. Provide ventilation.

Stability and Reactivity
【Incompatibilities】Oxidizing agents.
【Stability】Stable at room temperature in closed containers under normal storage and handling conditions.
【Decomposition】Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.