Product Identification
【Product Name】Niflumic acid ; 氟尼酸
【Synonyms】2-(a,a,a-Trifluoro-m-toluidino)nicotinic acid
【CAS】4394-00-7
【Formula】C13H9F3N2O2
【Molecular Weight】282.22000000000003
【EINECS】224-516-2
【RTECS】QT2999100
【RTECS Class】Drug; Reproductive Effector
【Merck】12,6620
【Beilstein/Gmelin】489360
【Beilstein Reference】5-22-13-00598

Physical and Chemical Properties
【Solubility in water】Slightly soluble
【Melting Point】204℃
【Boiling Point】378℃
【Vapor Pressure】2E-6 (25℃)
【pKa/pKb】1.68 (pKa)
【Heat Of Vaporization】66.0 kJ/mol
【Usage】Selective cyclooxygenase-2 (cox-2) inhibitor.

First Aid Measures
【Ingestion】If swallowed, wash out mouth with water provided person is conscious. Call a physician.
【Inhalation】If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
【Skin】In case of contact, immediately wash skin with soap and copious amounts of water.
【Eyes】In case of contact, immediately flush eyes with copious amounts of water for at least 15 minutes.

Handling and Storage
【Storage】Keep tightly closed. Store in a cool dry place.

Hazards Identification
【Inhalation】Material is irritating to mucous membranes and upper respiratory tract.
【Hazards】Emits toxic fumes under fire conditions.
【EC Risk Phrase】20/21/22 36/37/38
【EC Safety Phrase】26 36

Exposure Controls/Personal Protection
【Personal Protection】Rubber gloves. Chemical safety ggles.
【Respirators】vernment approved respirator.
【Exposure Effects】Harmful by inhalation, in contact with skin and if swallowed. Irritating to eyes, respiratory system and skin.

Fire Fighting Measures
【Flash Point】182℃
【Fire Fighting】Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Accidental Release Measures
【Small spills/leaks】Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity
【Incompatibilities】Strong oxidizing agents.
【Decomposition】Carbon monoxide, Carbon dioxide, Nitrogen oxides, Hydrogen fluoride.