Product Identification
【Product Name】2,3,4-Trifluorobenzenamine
【Synonyms】2,3,4-三氟苯胺
【CAS】3862-73-5
【Formula】C6H4F3N
【Molecular Weight】147.1
【EINECS】407-170-9
【RTECS】CY1211500
【RTECS Class】Primary Irritant
【Beilstein/Gmelin】3245609
【Beilstein Reference】4-12-00-01114
【EC Class】harmful, irritant
Physical and Chemical Properties
【Appearance】Brown liquid.
【Solubility in water】Slightly soluble
【Melting Point】14-15℃
【Boiling Point】174℃
【Vapor Pressure】1.3 (25℃)
【Density】1.39 g/cm3
【pKa/pKb】11.75 (pKb)
【Partition Coefficient】1.68
【Heat Of Vaporization】41.0 kJ/mol
【Vapor Density】5.07
【Refractive Index】1.49 (20℃)
First Aid Measures
【Ingestion】Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
【Inhalation】Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
【Skin】Get medical aid. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
【Eyes】Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Handling and Storage
【Storage】Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a cool, dry place. Store in a tightly closed container.
【Handling】Wash thoroughly after handling. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or flames.
Hazards Identification
【Inhalation】Aspiration may lead to pulmonary edema. Inhalation at high concentrations may cause CNS depression and asphixiation. Causes irritation of the mucous membrane and upper respiratory tract.
【Skin】Causes moderate skin irritation. May cause cyanosis of the extremities.
【Eyes】Causes moderate eye irritation. May cause chemical conjunctivitis and corneal damage.
【Ingestion】May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May form methemoglobin which in sufficient concentration causes cyanosis.
【Hazards】When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards.
【EC Risk Phrase】R 20/21/22 36/38
【EC Safety Phrase】S 26 36/37/39
【UN (DOT)】2810
Exposure Controls/Personal Protection
【Personal Protection】Eyes: Wear appropriate protective eyeglasses or chemical safety ggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
【Respirators】A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
【Exposure Effects】Absorption into the body leads to the formation of methemoglobin which in sufficient concentrations causes cyanosis.
Fire Fighting Measures
【Flash Point】68℃
【Fire Fighting】Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Combustible Liquid. Extinguishing media: Use water spray to cool fire-exposed containers. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
【Fire Potential】Combustible material: may burn but does not ignite ily.
Accidental Release Measures
【Small spills/leaks】Wash area with soap and water. Clean up spills immediately, using the appropriate protective equipment. Cover with sand, dry lime or soda ash and place in a closed container for disposal. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation.
Stability and Reactivity
【Stability】Stable under normal temperatures and pressures.
【Incompatibilities】Strong oxidizing agents, strong acids, acid chlorides, acid anhydrides.
【Decomposition】Nitrogen oxides, carbon monoxide, carbon dioxide, fluoride fumes, hydrogen fluoride.
【Combustion Products】Fire may produce irritating, corrosive and/or toxic gases.
Transport Information
【UN Number】2810
【Hazard Class】6.1
【Packing Group】I; II; III
【HS Code】2921 42 10