Product Identification
【Product Name】1-(2-Pyrimidyl)piperazine
【Synonyms】1-PP；1-(2-嘧啶基)哌嗪
【CAS】20980-22-7
【Formula】C8H12N4
【Molecular Weight】164.21
【EINECS】244-135-5
【RTECS】UV9702000
【RTECS Class】Drug
【Beilstein/Gmelin】151178
【Beilstein Reference】4-25-00-02083

Physical and Chemical Properties
【Appearance】After melting, clear yellow.
【Solubility in water】Very soluble
【Boiling Point】328℃
【Vapor Pressure】0.0002 (25℃)
【Density】1.07 g/cm3
【pKa/pKb】5.66 (pKb)
【Partition Coefficient】.49
【Heat Of Vaporization】57.0 kJ/mol

First Aid Measures
【Ingestion】Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
【Inhalation】Remove from exposure to fresh air immediately.
【Skin】Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
【Eyes】Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids.

Handling and Storage
【Storage】Store in a cool, dry place. Keep container closed when not in use.
【Handling】Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.

Exposure Controls/Personal Protection
【Personal Protection】Eyes: Wear safety glasses and chemical ggles if splashing is possible. Skin: Wear appropriate protective gloves and clothing to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
【Respirators】Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions.
【Exposure Effects】The toxicological properties of this material have not been investigated.

Fire Fighting Measures
【Flash Point】152℃
【Fire Fighting】Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.

Accidental Release Measures
【Small spills/leaks】Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal.

Stability and Reactivity
【Stability】Stable under normal temperatures and pressures.
【Incompatibilities】Strong oxidizing agents.
【Decomposition】Irritating and toxic fumes and gases.

Hazards Identification
【EC Risk Phrase】R 36/37/38
【EC Safety Phrase】S 26 36