Product Identification
【Product Name】Dimethyl 3-oxoglutarate ；3-氧代戊二酸二甲酯
【Synonyms】Dimethyl 1,3-acetonedicarboxylate
【CAS】1830-54-2
【Formula】C7H10O5
【Molecular Weight】174.15
【EINECS】217-385-8
【Beilstein/Gmelin】1366042
【Beilstein Reference】4-03-00-01817

Physical and Chemical Properties
【Appearance】Clear very slight yellow viscous liquid.
【Solubility in water】Slightly soluble
【Melting Point】16-17℃
【Boiling Point】262℃
【Vapor Pressure】0.01 (25℃)
【Density】1.18 g/cm3
【pKa/pKb】8.92 (pKa)
【Partition Coefficient】1.02
【Heat Of Vaporization】50.0 kJ/mol
【Vapor Density】6
【Refractive Index】1.4434 (20℃)

First Aid Measures
【Ingestion】Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
【Inhalation】Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
【Skin】Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
【Eyes】Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage
【Storage】Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Refrigerator (approx 4 C). Store protected from moisture.
【Handling】Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Do not allow contact with water. Keep from contact with moist air and steam.

Hazards Identification
【Ingestion】May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.
【Inhalation】May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
【Skin】May cause skin irritation.
【Eyes】May cause eye irritation.
【EC Risk Phrase】R 43
【EC Safety Phrase】S 24 36/37
【UN (DOT)】3334

Exposure Controls/Personal Protection
【Personal Protection】Eyes: Wear appropriate protective eyeglasses or chemical safety ggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
【Respirators】A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.

Fire Fighting Measures
【Flash Point】87℃
【Autoignition】343℃
【Fire Fighting】Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Do NOT get water inside containers. In case of fire, use carbon dioxide, dry chemical powder or appropriate foam.

Accidental Release Measures
【Small spills/leaks】Clean up spills immediately, using the appropriate protective equipment. Absorb spill using an absorbent, non-combustible material such as earth, sand, or vermiculite. Provide ventilation. Do not get water inside containers.

Stability and Reactivity
【Incompatibilities】Moisture.
【Stability】Stable under normal temperatures and pressures. Moisture sensitive.
【Decomposition】Carbon monoxide, carbon dioxide.

Transport Information
【UN Number】3334