Product Identification
【Product Name】3-Chlorobenzyl cyanide；间氯苯乙腈
【Synonyms】m-Chlorophenylacetonitrile
【CAS】1529-41-5
【Formula】C8H6ClN
【Molecular Weight】151.59
【EINECS】216-213-9
【RTECS】AL8240000
【RTECS Class】Other
【Beilstein/Gmelin】2042965
【Beilstein Reference】4-09-00-01675

Physical and Chemical Properties
【Appearance】Clear colorless to faint yellow liquid.
【Solubility in water】Insoluble
【Melting Point】11.5℃
【Boiling Point】270℃
【Vapor Pressure】0.007 (25℃)
【Density】1.1806 g/cm3 (30℃)
【Heat Of Vaporization】50.8 kJ/mol
【Vapor Density】5.2
【Refractive Index】1.554 (23.5℃)

First Aid Measures
【Ingestion】Never give anything by mouth to an unconscious person. Get medical aid. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Wash mouth out with water.
【Inhalation】Get medical aid immediately. Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. DO NOT use mouth-to-mouth respiration. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
【Skin】Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
【Eyes】Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage
【Storage】Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
【Handling】Wash thoroughly after handling. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use only in a chemical fume hood.

Hazards Identification
【Inhalation】May cause respiratory tract irritation. May cause cardiac abnormalities. Contains cyanide. May be metabolized to cyanide which in turns act by inhibiting cytochrome oxidase impairing cellular respiration. Inhalation at high concentrations may cause CNS depression and asphixiation.
【Skin】May cause skin irritation. May be metabolized to cyanide which in turn acts by inhibiting cytochrome oxidase impairing cellular respiration.
【Eyes】May cause eye irritation.
【Ingestion】May cause irritation of the digestive tract. May cause cardiac disturbances. May cause central nervous system depression. Metabolism may release cyanide, which may result in headache, dizziness, weakness, collapse, unconsciousness and possible death. Contains cyanide.
【Hazards】When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards.
【EC Risk Phrase】R 23/24/25 36/38
【EC Safety Phrase】S 26 36/37/39 45
【UN (DOT)】2810

Exposure Controls/Personal Protection
【Personal Protection】Eyes: Wear appropriate protective eyeglasses or chemical safety ggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
【Respirators】Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
【Exposure Effects】May be metabolized to cyanide which in turn acts by inhibiting cytochrome oxidase impairing cellular respiration. Chronic exposure to cyanide solutions may lead to the development of a cyanide rash, characterized by itching, and by macular, papular, and vesicular eruptions, and may be accompanied by secondary infections.

Fire Fighting Measures
【Flash Point】108℃
【Fire Fighting】Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Combustion generates toxic fumes. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Wear appropriate protective clothing to prevent contact with skin and eyes. Wear a self-contained breathing apparatus (SCBA) to prevent contact with thermal decomposition products. Runoff from fire control or dilution water may cause pollution. Extinguishing media: For small fires, use dry chemical, carbon dioxide, or water spray. For large fires, use dry chemical, carbon dioxide, alcohol-resistant foam, or water spray. Cool containers with flooding quantities of water until well after fire is out.
【Fire Potential】Combustible material: may burn but does not ignite ily.

Accidental Release Measures
【Small spills/leaks】Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Provide ventilation.

Stability and Reactivity
【Stability】Stable at room temperature in closed containers under normal storage and handling conditions.
【Incompatibilities】Strong acids, strong bases, strong oxidizing agents, strong reducing agents.
【Decomposition】Hydrogen chloride, hydrogen cyanide, nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.
【Combustion Products】Fire may produce irritating, corrosive and/or toxic gases.

Transport Information
【UN Number】2810
【Hazard Class】6.1
【Packing Group】I; II; III