Product Identification
【Product Name】4-Hydroxy-2-mercaptopyrimidine
【Synonyms】2-Thio-6-oxypyrimidine 2-硫脲嘧
【CAS】141-90-2
【Formula】C4H4N2OS
【Molecular Weight】128.15
【EINECS】205-508-8
【RTECS】YR1575000
【RTECS Class】Tumorigen; Drug; Mutagen; Reproductive Effector; Human Data
【Merck】12,9504
【Beilstein/Gmelin】112227
【Beilstein Reference】5-24-06-00361

Physical and Chemical Properties
【Appearance】Minute crystals, prisms, or white or pale cream-colored powder. Odorless.
【Solubility in water】Slightly soluble
【Melting Point】340℃
【Partition Coefficient】.04
【Usage】Chemical intermediate for iothiouracil sodium- an antithyroid agent.

First Aid Measures
【Ingestion】Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
【Inhalation】Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
【Skin】Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
【Eyes】Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage
【Storage】

Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Hormones and antibiotics room.
【Handling】Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.

Hazards Identification
【Inhalation】May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. Exposure to high concentrations of mercaptans can produce unconsciousness with cyanosis, cold extremities and rapid pulse. Mercaptans may cause nausea and headache.
【Skin】May cause skin irritation.
【Eyes】May cause eye irritation.
【Ingestion】May cause irritation of the digestive tract. May cause liver damage. The toxicological properties of this substance have not been fully investigated. Mercaptans may cause nausea and headache. Exposure to high concentrations of mercaptans can produce unconsciousness with cyanosis, cold extremities and rapid pulse.
【EC Risk Phrase】R 40
【EC Safety Phrase】S 22 36/37

Exposure Controls/Personal Protection
【Personal Protection】Eyes: Wear appropriate protective eyeglasses or chemical safety ggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
【Respirators】A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
【Exposure Effects】Chronic ingestion may cause liver damage. Reproductive effects have been reported in humans.
【Poison Class】1*

Fire Fighting Measures
【Autoignition】570℃
【Fire Fighting】Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.

Accidental Release Measures
【Small spills/leaks】Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation.

Stability and Reactivity
【Disposal Code】3
【Incompatibilities】Oxidizing agents.
【Stability】Stable under normal temperatures and pressures.
【Decomposition】Nitrogen oxides, carbon monoxide, oxides of sulfur, irritating and toxic fumes and gases, carbon dioxide.

Transport Information
【HS Code】2933 59 95