Product Identification
【Product Name】4-(Chloromethyl)benzoyl chloride
【Synonyms】对氯甲基苯甲酰氯
【CAS】876-08-4
【Formula】C8H6Cl2O
【Molecular Weight】189.04
【EINECS】212-881-0
【Beilstein/Gmelin】1817680
【Beilstein Reference】4-09-00-01744
Physical and Chemical Properties
【Appearance】White crystals crystals.
【Solubility in water】Insoluble
【Melting Point】30~31℃
【Boiling Point】276℃
【Vapor Pressure】0.005 (25 C)
【Density】1.3034 g/cm3 (20 C)
【Partition Coefficient】2.48
【Heat Of Vaporization】57.6 kJ/mol
【Refractive Index】1.5700 (20℃)
First Aid Measures
【Ingestion】Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Get medical aid immediately.
【Inhalation】Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. DO NOT use mouth-to-mouth respiration. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
【Skin】Get medical aid. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.
【Eyes】Get medical aid immediately. Do NOT allow victim to rub or keep eyes closed. Extensive irrigation is required (at least 30 minutes).
Handling and Storage
【Storage】Keep away from heat, sparks, and flame. Keep away from sources of ignition. Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances. Corrosives area. Store protected from moisture.
【Handling】Wash thoroughly after handling. Use with adequate ventilation. Use spark-proof tools and explosion proof equipment. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. Do not allow contact with water. Discard contaminated shoes. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or flames. Keep from contact with moist air and steam.
Hazards Identification
【Inhalation】Causes chemical burns to the respiratory tract. Inhalation may be fatal as a result of spasm, inflammation, edema of the larynx and bronchi, chemical pneumonitis and pulmonary edema. Aspiration may lead to pulmonary edema. May cause systemic effects. Inhalation at high concentrations may cause CNS depression and asphixiation.
【Skin】Causes skin burns. May cause cyanosis of the extremities. May cause skin rash (in milder cases), and cold and clammy skin with cyanosis or pale color.
【Eyes】Causes eye burns. Lachrymator. May cause chemical conjunctivitis and corneal damage.
【Ingestion】May cause severe and permanent damage to the digestive tract. Causes gastrointestinal tract burns. May cause perforation of the digestive tract. May cause systemic effects.
Exposure Controls/Personal Protection
【Personal Protection】Eyes: Wear appropriate protective eyeglasses or chemical safety ggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
【Respirators】A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
【Exposure Effects】Effects may be delayed.
Fire Fighting Measures
【Flash Point】92℃
【Fire Fighting】Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Will burn if involved in a fire. Use water spray to keep fire-exposed containers cool. Containers may explode when heated. Extinguishing media: Use water spray to cool fire-exposed containers. Use foam, dry chemical, or carbon dioxide. Use agent most appropriate to extinguish fire. Do NOT get water inside containers.
Accidental Release Measures
【Small spills/leaks】Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation. Do not get water inside containers.
Stability and Reactivity
【Incompatibilities】Moisture, strong oxidizing agents, strong bases.
【Stability】Stable at room temperature in closed containers under normal storage and handling conditions.
【Decomposition】Hydrogen chloride, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.