Product Identification
【Product Name】2-Chloro-1,4-dihydroxybenzene
【Synonyms】Chloroquinol ，氯氢醌
【CAS】615-67-8
【Formula】C6H5ClO2
【Molecular Weight】144.56
【EINECS】210-442-8
【RTECS】MX4800000
【RTECS Class】Reproductive Effector
【Beilstein/Gmelin】636835
【Beilstein Reference】4-06-00-05767

Physical and Chemical Properties
【Appearance】White to light-tan fine crystals.
【Solubility in water】Slightly soluble
【Melting Point】100
【Boiling Point】263
【Vapor Pressure】0.0065 (25 C)
【pKa/pKb】9.09 (pKa)
【Partition Coefficient】1.52
【Heat Of Vaporization】52.1 kJ/mol
【Heat Of Combustion】-2711 kJ/mol
【Usage】Photographic developer, organic intermediate, in dyestuffs, bactericide.

First Aid Measures
【Ingestion】Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
【Inhalation】Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. Get medical aid. DO NOT use mouth-to-mouth respiration. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
【Skin】Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
【Eyes】Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage
【Storage】Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
【Handling】Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid breathing dust, vapor, mist, or gas. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.

Hazards Identification
【Inhalation】Dust is irritating to the respiratory tract. The toxicological properties of this substance have not been fully investigated.
【Skin】May cause skin irritation.
【Eyes】May cause eye irritation.
【Ingestion】May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.

Exposure Controls/Personal Protection
【Personal Protection】Eyes: Wear appropriate protective eyeglasses or chemical safety ggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
【Respirators】Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
【Exposure Effects】Dizziness, headache and delirium have been reported with hydroquinone exposure. Quinone has cause paralysis of the medullary centers and coma. Both quinone and hydroquinone may cause seizures. In rat studies, maternal toxic effects from exposure to hydroquinone included changes in the ovaries, fallopian tubes, and menstrual cycle. Post-implantation mortality was also observed in rat studies.
Observed paternal toxic effects from exposure to hydroquinone included changes in the testes, epididymis, sperm duct, prostate, seminal vesicle, Cowper's gland, accessory glands, and male fertility index.
Exposure to hydroquinone produced skeletal malformations in chickens and ocular and skeletal malformations in rabbits.

Fire Fighting Measures
【Flash Point】120
【Fire Fighting】Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Runoff from fire control or dilution water may cause pollution. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.

Accidental Release Measures
【Small spills/leaks】Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation.

Stability and Reactivity
【Incompatibilities】Oxidizing agents, strong bases.
【Stability】Stable under normal temperatures and pressures.
【Decomposition】Hydrogen chloride, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.