Product Identification
【Product Name】1,3-Dichloro-4-nitrobenzene
【Synonyms】2,4-Dichloro-1-nitrobenzene ；2,4-二氯硝基苯
【CAS】611-06-3
【Formula】C6H3Cl2NO2
【Molecular Weight】192
【EINECS】210-248-3
【RTECS】CZ5420000
【RTECS Class】Mutagen
【Beilstein/Gmelin】1451655
【Beilstein Reference】4-05-00-00726
【EC Class】harmful, sensitizing, dangerous for the environment

Physical and Chemical Properties
【Appearance】Light yellow needles or amber crystalline solid.
【Solubility in water】188 g/L
【Melting Point】28-31℃
【Boiling Point】258℃
【Vapor Pressure】0.75 (45℃)
【Density】1.4434 g/cm3 (75℃)
【Partition Coefficient】3.07
【Usage】Chemical intermediate for diazoxide (an antihypertensive agent).
【Vapor Density】6.6
【Refractive Index】1.5512 (78.1℃)

First Aid Measures
【Ingestion】Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
【Inhalation】Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. DO NOT use mouth-to-mouth respiration.
【Skin】Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
【Eyes】Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage
【Storage】Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
【Handling】Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.

Hazards Identification
【Inhalation】May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
【Skin】May cause skin irritation.
【Eyes】May cause eye irritation.
【Ingestion】May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.
【Hazards】Containers may explode when heated.
【EC Risk Phrase】R 23/24/25 33 36/38
【EC Safety Phrase】S 28 36/37/39 45
【UN (DOT)】1578

Exposure Controls/Personal Protection
【Personal Protection】Eyes: Wear appropriate protective eyeglasses or chemical safety ggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
【Respirators】A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
【Exposure Effects】Rapid heart rate, rapid breathing, abnormally low blood pressure, and respiratory depression may occur. Headache, dizziness, lethargy, and coma are possible. Nitrobenzene is a possible animal teratogen.

Fire Fighting Measures
【Flash Point】152℃
【Autoignition】500℃
【Fire Fighting】Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
【Fire Potential】This chemical is combustible.

Accidental Release Measures
【Small spills/leaks】Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.

Stability and Reactivity
【Disposal Code】3
【Incompatibilities】Oxidizing agents.
【Stability】Stable under normal temperatures and pressures.
【Decomposition】Hydrogen chloride, nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen.
【Combustion Products】Fire may produce irritating, corrosive and/or toxic gases.

Transport Information
【UN Number】1578
【Hazard Class】6.1
【Packing Group】II
【HS Code】2904 90 85