Product Identification
【Product Name】4-(Trifluoromethyl)benzonitrile
【Synonyms】p-Cyanobenzotrifluoride 对三氟甲基苯腈
【CAS】455-18-5
【Formula】C8H4F3N
【Molecular Weight】171.12
【EINECS】207-239-1
【Beilstein/Gmelin】2046478
【Beilstein Reference】4-09-00-01743

Physical and Chemical Properties
【Appearance】Colorless to white crystals.
【Solubility in water】Insoluble
【Melting Point】35-38℃
【Boiling Point】180℃
【Vapor Pressure】0.8 (25℃)
【Density】1.2784 g/cm3 (20 C)
【Partition Coefficient】2.63
【Heat Of Vaporization】41.9 kJ/mol
【Refractive Index】1.46 (20℃)

First Aid Measures
【Ingestion】Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
【Inhalation】Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
【Skin】Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
【Eyes】Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage
【Storage】Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
【Handling】Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.

Hazards Identification
【Ingestion】May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.
【Inhalation】May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
【Skin】May cause skin irritation.
【Eyes】May cause eye irritation.
【Hazards】Contact with metals may evolve flammable hydrogen gas.
【EC Risk Phrase】R 20/21/22
【EC Safety Phrase】S 36/37
【UN (DOT)】2811

Exposure Controls/Personal Protection
【Personal Protection】Eyes: Wear appropriate protective eyeglasses or chemical safety ggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
【Respirators】A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.

Fire Fighting Measures
【Flash Point】71℃
【Fire Fighting】Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Dusts may be combustible when exposed to heat, flame, or oxidizing agents. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
【Fire Potential】Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.

Accidental Release Measures
【Small spills/leaks】Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.

Stability and Reactivity
【Disposal Code】3
【Incompatibilities】Oxidizing agents, reducing agents.
【Stability】Stable under normal temperatures and pressures.
【Decomposition】Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, hydrogen fluoride, nitrogen.
【Combustion Products】Fire may produce irritating, corrosive and/or toxic gases.

Transport Information
【UN Number】2811
【Hazard Class】6.1
【Packing Group】I; II; III
【HS Code】2926 90 95