Product Identification
【Product Name】Genistein；金雀异黄素；金雀异黄酮
【Synonyms】4',5,7-Trihydroxyisoflavone
【CAS】446-72-0
【Formula】C15H10O5
【Molecular Weight】270.24
【EINECS】207-174-9
【RTECS】NR2392000
【RTECS Class】Tumorigen; Drug; Mutagen; Reproductive Effector
【Merck】13,4402
【Beilstein/Gmelin】263823
【Beilstein Reference】5-18-04-00594

Physical and Chemical Properties
【Appearance】odorless yellow-white powder
【Solubility in water】Insoluble
【Melting Point】297-298℃
【pKa/pKb】7.08 (pKa)
【Partition Coefficient】2.84
【Usage】Chemical probe to explore signal transduction pathways.

First Aid Measures
【Ingestion】Get medical aid. Wash mouth out with water.
【Inhalation】Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
【Skin】Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
【Eyes】Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage
【Storage】Store in a tightly closed container. Refrigerator (approx 4 C).
【Handling】Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.

Hazards Identification
【Ingestion】May cause irritation of the digestive tract. May be harmful if swallowed.
【Inhalation】May cause respiratory tract irritation. May be harmful if inhaled.
【Skin】May cause skin irritation. May be harmful if absorbed through the skin. May cause allergic dermatitis called nickel itch. Symptoms may include burns and ulceration of skin.
【Eyes】May cause eye irritation.
【EC Risk Phrase】R 36/37/38
【EC Safety Phrase】S 26 36

Exposure Controls/Personal Protection
【Personal Protection】Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
【Respirators】Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Fire Fighting Measures
【Fire Fighting】Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam.

Accidental Release Measures
【Small spills/leaks】Vacuum or sweep up material and place into a suitable disposal container.

Stability and Reactivity
【Stability】No data.
【Incompatibilities】Strong oxidizing agents.
【Decomposition】Carbon monoxide, carbon dioxide.