Product Identification
【Product Name】Ethyl 3-oxo-4,4,4-trifluoroacetoacetate
【Synonyms】1-Ethoxy-4,4,4-trifluorobutane-1,3-dione 三氟乙酰乙酸乙酯
【CAS】372-31-6
【Formula】C6H7F3O3
【Molecular Weight】184.12
【EINECS】206-750-7
【Beilstein/Gmelin】608353
【Beilstein Reference】4-03-00-01548
【EC Class】flammable

Physical and Chemical Properties
【Appearance】Clear, colorless liquid.
【Solubility in water】Insoluble
【Melting Point】-39
【Boiling Point】131
【Density】1.2586 g/cm3 (15.5 C)
【pKa/pKb】7.63 (pKa)
【Refractive Index】1.3783 (15 C)

First Aid Measures
【Ingestion】If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
【Inhalation】Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
【Skin】Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Remove contaminated clothing and shoes.
【Eyes】Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage
【Storage】Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Flammables-area.
【Handling】Wash thoroughly after handling. Use with adequate ventilation. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or flames.

Hazards Identification
【Ingestion】May cause gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated.
【Inhalation】May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. Vapors may cause dizziness or suffocation.
【Skin】May cause skin irritation. The toxicological properties of this material have not been fully investigated.
【Eyes】May cause eye irritation. The toxicological properties of this material have not been fully investigated.
【Hazards】Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will sp along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers.
【EC Risk Phrase】R 10 22 52/53
【EC Safety Phrase】S 16 26 36 61
【UN (DOT)】1993

Exposure Controls/Personal Protection
【Personal Protection】Eyes: Wear appropriate protective eyeglasses or chemical safety ggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
【Respirators】Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Fire Fighting Measures
【Flash Point】29
【Fire Fighting】Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Will burn if involved in a fire. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. Extinguishing media: Use water spray to cool fire-exposed containers. Water may be ineffective. Use agent most appropriate to extinguish fire. Do NOT use straight streams of water. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
【Fire Potential】HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames.

Accidental Release Measures
【Small spills/leaks】Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation. A vapor suppressing foam may be used to reduce vapors.

Stability and Reactivity
【Disposal Code】2
【Incompatibilities】Oxidizing agents.
【Stability】Stable under normal temperatures and pressures.
【Decomposition】Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, hydrogen fluoride.
【Combustion Products】Fire may produce irritating, corrosive and/or toxic gases.

Transport Information
【UN Number】1993
【Hazard Class】3
【Packing Group】I; II; III
【HS Code】2918 30 00