Product Identification
【Product Name】Caffeic acid 咖啡酸
【Synonyms】
3-(3,4-Dihydroxyphenyl)-2-proic acid
3,4-Dihydroxybenzeneacrylic acid
3,4-Dihydroxycinnamic acid
4-(2-Carboxyethenyl)-1,2-dihydroxybenzene
4-(2'-Carboxyvinyl)-1,2-dihydroxybenzene
【CAS】331-39-5
【Formula】C9H8O4
【Molecular Weight】180.16
【EINECS】206-361-2
【RTECS】GD8950000
【RTECS Class】Tumorigen; Mutagen; Reproductive Effector; Natural Product
【Merck】13,1635
【Beilstein/Gmelin】2210883
【Beilstein Reference】2-10-00-00294
【EC Class】carcinogenic
Physical and Chemical Properties
【Appearance】Yellow prisms or plates (from chloroform or ligroin) or pale yellow granules. Alkaline solutions turn from yellow to orange.
【Solubility in water】Very soluble
【Melting Point】234 - 237
【Boiling Point】366
【pKa/pKb】4.04 (pKa)
【Partition Coefficient】1.15
【Usage】Inhibitor of poly(ethylene glycol) oxidation.
First Aid Measures
【Ingestion】If victim is conscious and alert, give 2-4 cupfuls of milk or water. Get medical aid immediately.
【Inhalation】Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
【Skin】Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
【Eyes】Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Handling and Storage
【Storage】Store in a cool, dry place. Keep container closed when not in use.
【Handling】Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.
Hazards Identification
【Inhalation】The toxicological properties of this substance have not been fully investigated.
【Skin】No information regarding skin irritation and other potential effects was found.
【Eyes】May cause eye irritation. No information regarding eye irritation and other potential effects was found.
【Ingestion】The toxicological properties of this substance have not been fully investigated.
【EC Risk Phrase】R 36/37/38 40
【EC Safety Phrase】S 22 26 36/37/39
Exposure Controls/Personal Protection
【Personal Protection】Eyes: Wear safety glasses and chemical ggles if splashing is possible. Skin: Wear appropriate protective gloves and clothing to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
【Respirators】Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions.
【Exposure Effects】The toxological properties of this substance have not been fully investigated.
Fire Fighting Measures
【Fire Fighting】Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.
【Fire Potential】This material is probably combustible.
Accidental Release Measures
【Small spills/leaks】Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal.
Stability and Reactivity
【Disposal Code】4
【Stability】Stable under normal temperatures and pressures.
【Incompatibilities】Strong oxidizing agents - strong bases.
【Decomposition】Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.
Transport Information
【HS Code】2918 29 90