丙二酸二甲酯安全技术说明书
Product Identification
【Product Name】Methyl malonate
【Synonyms】Dimethyl 1,3-propanedioate
【CAS】108-59-8
【Formula】C5H8O4
【Molecular Weight】132.12
【EINECS】203-597-8
【RTECS】OO0950000
【RTECS Class】Primary Irritant
【Merck】12,6169
【Beilstein/Gmelin】774261
【Beilstein Reference】4-02-00-01880

Physical and Chemical Properties
【Appearance】Clear, colorless liquid.
【Solubility in water】Very soluble
【Melting Point】-62℃
【Boiling Point】181℃
【Vapor Pressure】45 (101℃)
【Density】1.1722 g/cm3 (0℃)
【pKa/pKb】11.79 (pKa)
【Heat Of Vaporization】61.88 kJ/mol
【Heat Of Combustion】-2313 kJ/mol
【Usage】A common reagent for organic synthesis.
【Refractive Index】1.4149 (20℃)

First Aid Measures
【Ingestion】Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
【Inhalation】Remove from exposure to fresh air immediately.
【Skin】Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
【Eyes】Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids.

Handling and Storage
【Storage】Store in a cool, dry place. Keep container closed when not in use.
【Handling】Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.

Exposure Controls/Personal Protection
【Personal Protection】Eyes: Wear safety glasses and chemical ggles if splashing is possible. Skin: Wear appropriate protective gloves and clothing to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
【Respirators】Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions.
【Exposure Effects】The toxicological properties of this material have not been investigated.
【Poison Class】4

Fire Fighting Measures
【Flash Point】90℃
【Autoignition】440℃
【Fire Fighting】Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire.
【Upper exp. limit】17.4
【Lower exp. limit】1.3

Accidental Release Measures
【Small spills/leaks】Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Clean up spills immediately, using the appropriate protective equipment.

Stability and Reactivity
【Disposal Code】1
【Incompatibilities】Acids - bases - oxidizing agents - reducing agents.
【Stability】Stable under normal temperatures and pressures.
【Decomposition】Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Transport Information
【HS Code】2917 19 10

Hazards Identification
【EC Safety Phrase】S 23 24/25